Eugenio Gaudio Selected Research

MRT-92

1/2021

Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.

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Eugenio Gaudio Research Topics

Disease

71	Neoplasms (Cancer) 05/2024 - 12/2006
41	Fibrosis (Cirrhosis) 01/2024 - 10/2004
29	Lymphoma (Lymphomas) 05/2024 - 01/2013
28	Cholangiocarcinoma 06/2024 - 09/2006
23	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 02/2009
20	Liver Diseases (Liver Disease) 01/2023 - 04/2007
18	Cholestasis 10/2023 - 07/2002
16	Inflammation (Inflammations) 03/2024 - 02/2006
16	Non-alcoholic Fatty Liver Disease 01/2023 - 12/2012
12	Hyperplasia 01/2022 - 05/2007
8	B-Cell Lymphoma (Lymphoma, B Cell) 05/2024 - 04/2015
7	Sclerosing Cholangitis 01/2023 - 01/2016
6	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2023 - 04/2004
5	Lung Neoplasms (Lung Cancer) 01/2019 - 05/2008
4	Melanoma (Melanoma, Malignant) 10/2022 - 01/2013
4	Leukemia 10/2020 - 01/2013
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/2018 - 03/2015
4	Colitis 07/2018 - 07/2002
4	Breast Neoplasms (Breast Cancer) 07/2013 - 09/2006
3	Cystic Fibrosis (Mucoviscidosis) 01/2023 - 04/2010
3	Fatty Liver 07/2021 - 08/2015
3	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 02/2016
3	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2016 - 02/2008
3	Cysts 11/2016 - 02/2008
3	Insulin Resistance 01/2016 - 10/2013
3	Neoplasm Metastasis (Metastasis) 07/2012 - 07/2010
3	Extrahepatic Cholestasis 07/2010 - 01/2010
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 02/2024 - 01/2019
2	Ataxia Telangiectasia (Louis Bar Syndrome) 11/2023 - 01/2012
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2023 - 01/2013
2	T-Cell Lymphoma (Lymphoma, T Cell) 11/2023 - 10/2020
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 06/2023 - 01/2016
2	Cholangitis 01/2023 - 01/2023

Drug/Important Bio-Agent (IBA)

33	Proteins (Proteins, Gene)FDA Link 03/2024 - 12/2006
13	secretin receptorIBA 01/2023 - 04/2010
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 04/2006
11	Secretin FDA Link 01/2023 - 04/2010
10	CollagenIBA 01/2022 - 08/2009
9	MelatoninIBA 01/2022 - 10/2011
7	EnzymesIBA 01/2023 - 11/2008
6	Biomarkers (Surrogate Marker)IBA 03/2024 - 04/2012
5	Immunoconjugates (Immunoconjugate)IBA 05/2024 - 01/2019
5	DNA (Deoxyribonucleic Acid)IBA 02/2024 - 02/2008
5	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 05/2010
5	Peptides (Polypeptides)IBA 01/2023 - 10/2012
5	Messenger RNA (mRNA)IBA 01/2023 - 05/2010
5	Bicarbonates (Hydrogen Carbonate)IBA 01/2023 - 03/2013
5	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2023 - 02/2008
5	nasIBA 01/2022 - 12/2012
5	MicroRNAs (MicroRNA)IBA 01/2020 - 04/2012
5	Hormones (Hormone)IBA 01/2019 - 07/2008
5	Protein Tyrosine PhosphatasesIBA 05/2018 - 06/2006
4	LigandsIBA 12/2023 - 07/2012
4	Phosphotransferases (Kinase)IBA 11/2023 - 07/2013
4	Chloride-Bicarbonate AntiportersIBA 01/2023 - 04/2010
4	fragile histidine triad proteinIBA 10/2022 - 05/2008
4	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2020 - 05/2008
4	LipidsIBA 01/2020 - 10/2012
4	CytokinesIBA 01/2020 - 01/2014
4	MucinsIBA 01/2019 - 06/2012
4	Transforming Growth Factors (Transforming Growth Factor)IBA 07/2018 - 01/2017
3	Cytotoxins (Cytolysins)IBA 02/2024 - 01/2010
3	LipopolysaccharidesIBA 12/2023 - 08/2015
3	Taurocholic Acid (Sodium Taurocholate)IBA 01/2023 - 05/2010
3	Histamine (Histamine Dihydrochloride)FDA Link 01/2023 - 06/2010
3	IronIBA 12/2022 - 04/2020
3	Therapeutic UsesIBA 12/2022 - 10/2017
3	Insulin (Novolin)FDA Link 06/2021 - 01/2015
3	Histone Deacetylase InhibitorsIBA 01/2021 - 03/2015
3	AdipokinesIBA 01/2020 - 12/2012
3	Agammaglobulinaemia Tyrosine KinaseIBA 12/2019 - 09/2016
3	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 05/2008
3	Transcription Factors (Transcription Factor)IBA 01/2019 - 12/2006
3	Arylalkylamine N-AcetyltransferaseIBA 01/2019 - 11/2014
3	Ferredoxins (Ferredoxin)IBA 01/2019 - 05/2008
3	OTX015IBA 12/2018 - 04/2015
3	ChromatinIBA 12/2018 - 03/2015
3	Cyclin D1IBA 09/2016 - 01/2013
3	Transforming Growth Factor beta (TGF-beta)IBA 01/2014 - 02/2006
3	WW Domain-Containing OxidoreductaseIBA 07/2010 - 10/2007
3	Estrogen ReceptorsIBA 02/2008 - 12/2004
3	Estrogens (Estrogen)FDA Link 02/2008 - 07/2002
2	idelalisibIBA 12/2023 - 01/2023
2	Lapatinib (GW572016)FDA Link 12/2023 - 01/2023
2	copanlisibIBA 11/2023 - 10/2020
2	Rituximab (Mabthera)FDA Link 11/2023 - 09/2016
2	Monoclonal AntibodiesIBA 11/2023 - 09/2016
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 10/2023 - 01/2014
2	OxazolesIBA 06/2023 - 10/2020
2	CholesterolIBA 01/2023 - 01/2023
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 04/2020
2	Sirolimus (Rapamycin)FDA Link 01/2023 - 06/2019
2	SodiumIBA 01/2023 - 07/2018

Therapy/Procedure

33	Therapeutics 06/2024 - 04/2007
13	Ligation 04/2017 - 08/2005
7	Liver Transplantation 01/2022 - 10/2004
6	Drug Therapy (Chemotherapy) 09/2023 - 11/2008
5	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2022 - 07/2013
3	Transplantation 06/2021 - 12/2014
3	Radiotherapy 02/2016 - 11/2008